Founded as a city cemetery in 1865, grave sites in the Jewish section date from the 1880s. Among the early Jewish pioneers buried here are Berman and Rose Weintraub, who operated a successful grocery business in 1900 and assisted fellow Romanian settlers. Also buried here are Abraham and Annie Einhorn, initially helped by the Weintraubs, who later operated the Big Door Grocery.

The grave of Joe Pearlman, one of the pioneers of Duval Street, who was president of the Jewish congregation for 25 years is located here. Others are Jacob Markowitz, Isadore Appelrouth, Rubin and Lillie Appel, Theodore and Elka Holtsberg, and brothers Jake and David Aronovitz and their wives, both named Celia. All had settled in Key West by the early 1900s.

Information courtesy of Florida Division of Historical Resources, a division of Florida Department of State.